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Fatal insomnia is an extremely rare neurodegenerative prion disease that results in trouble sleeping as its hallmark symptom. [2] The majority of cases are familial ( fatal familial insomnia [FFI]), stemming from a mutation in the PRNP gene, with the remainder of cases occurring sporadically ( sporadic fatal insomnia [sFI]).
Proctalgia fugax. Specialty. General surgery. Proctalgia fugax, a variant of levator ani syndrome, is a severe, episodic pain in the regions of the rectum and anus. [1] It can be caused by cramping of the levator ani muscle, particularly in the pubococcygeal part. [2]
Excessive daytime sleepiness ( EDS) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep. EDS can be considered as a broad condition encompassing several sleep disorders where increased sleep is a symptom, or as a symptom of another ...
Paroxysmal nocturnal dyspnea or paroxysmal nocturnal dyspnoea ( PND) is an attack of severe shortness of breath and coughing that generally occurs at night. [1] It usually awakens the person from sleep, and may be quite frightening. [2] PND, as well as simple orthopnea, may be relieved by sitting upright at the side of the bed with legs ...
Exploding head syndrome. Exploding head syndrome ( EHS) is an abnormal sensory perception during sleep in which a person experiences auditory hallucinations that are loud and of short duration when falling asleep or waking up. [2] [4] The noise may be frightening, typically occurs only occasionally, and is not a serious health concern. [2]
Brunner syndrome. This condition is inherited in an X-linked recessive manner. Brunner syndrome is a rare genetic disorder associated with a mutation in the MAOA gene. It is characterized by lower than average IQ (typically about 85), problematic impulsive behavior (such as pyromania, hypersexuality and violence), sleep disorders and mood swings.