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2. Clinical study design - Wikipedia

   en.wikipedia.org/wiki/Clinical_study_design

   Clinical study design is the formulation of trials and experiments, as well as observational studies in medical, clinical and other types of research (e.g., epidemiological) involving human beings. [ 1] The goal of a clinical study is to assess the safety, efficacy, and / or the mechanism of action of an investigational medicinal product (IMP ...

3. Clinical trial - Wikipedia

   en.wikipedia.org/wiki/Clinical_trial

   A clinical trial participant receives an injection. Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further ...

4. Phases of clinical research - Wikipedia

   en.wikipedia.org/wiki/Phases_of_clinical_research

   The phases of clinical research are the stages in which scientists conduct experiments with a health intervention to obtain sufficient evidence for a process considered effective as a medical treatment. [ 1] For drug development, the clinical phases start with testing for drug safety in a few human subjects, then expand to many study ...

5. Clinical research - Wikipedia

   en.wikipedia.org/wiki/Clinical_research

   Clinical research is a branch of medical research that involves people and aims to determine the effectiveness ( efficacy) and safety of medications, devices, diagnostic products, and treatment regimens intended for improving human health. [1] [2] These research procedures are designed for the prevention, treatment, diagnosis or understanding ...

6. Hierarchy of evidence - Wikipedia

   en.wikipedia.org/wiki/Hierarchy_of_evidence

   Evidence-based practices. A hierarchy of evidence, comprising levels of evidence ( LOEs ), that is, evidence levels ( ELs ), is a heuristic used to rank the relative strength of results obtained from experimental research, especially medical research. There is broad agreement on the relative strength of large-scale, epidemiological studies.

7. Preclinical development - Wikipedia

   en.wikipedia.org/wiki/Preclinical_development

   Preclinical development. In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.